Epileptic Focus Localization – ICSL

For many epilepsy patients, only surgical removal of the epileptogenic zone can successfully control their seizures. Surgical success depends upon accurate localization of the epileptic activity. Currently, electroencephalography (EEG) is the most widely used tool for localizing the epileptogenic zone, but it suffers from low spatial resolution. By combining EEG with functional magnetic resonance imaging (fMRI), which has higher spatial resolution, better localization may be possible. The main focus of this research is combining features of EEG and fMRI and using classification methodologies to distinguish between normal brain regions and epileptogenic regions. The best combination of features is found using genetic programming. Those features are then used to classify all areas of the brain as either normal or epileptogenic.